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Wen-Wei Sung, M.D., Ph.D., Professor Wen-Wei Sung, M.D., Ph.D., Professor

學歷 經歷 專長 學術研討 門診表 其他
  • 1. M.D., School of Medicine, Chung Shan Medical University (M.D.-Ph.D. Program)
  • 2. Ph.D., Institute of Medicine, and Institute of Medical & Molecular Toxicology, Chung Shan Medical University
  • 3. Ph.D., Institute of Medical & Molecular Toxicology, Chung Shan Medical University
  • 4.
  • 1. Professor, School of Medicine, Chung Shan Medical University
  • 2. Professor, Institute of Medicine, Chung Shan Medical University
  • 3. Board-Certified Urologist, Taiwan Urological Association
  • 4. Member, Taiwan Urological Association, European Association of Urology, Korean Urological Association, and International Urological Association
  • 5. Member, Taiwanese Association for Andrology and Sexual Medicine; Taiwanese Continence Society; Taiwan Urological Oncology Association
  • 6. Member, American Association for Cancer Research
  • 7. Member, Education Committee, Taiwan Urological Association
  • 8. Executive Editor, Journal Committee, Taiwan Urological Association
  • 9. Member, Youth Affairs Committee, Taiwan Urological Association
  • 10. Completed training at Chung Shan Medical University Hospital and the Korean Urological Association
  • 11. Representative of Taiwan in the European Association of Urology (EAU) exchange program
  • 12. Short-term exchange at University Hospital Tübingen, Germany
  • 13. Short-term exchange at the European Institute of Oncology, Italy
  • 14. Peer reviewer for two top-tier journals worldwide (in general and clinical medicine fields, top 1% globally)
  • 15. Recipient of the Research Grant Award for colleges and universities from the National Science and Technology Council
  • 16. Ministry of Education Scholarship Awardee for Physician-Scientists
  • 17. Young Physician Award, Taichung Medical Association
  • 18. Recognized as an Outstanding Teacher at Chung Shan Medical University (University-wide), Outstanding Teacher of the College of Medicine, and Excellent Teacher of the School of Medicine
  • 19. New Investigator Paper Award, College of Medicine, Chung Shan Medical University
  • 20. Outstanding Research Award, Chung Shan Medical University Hospital
  • 21. Excellent Clinical Teacher, Chung Shan Medical University Hospital
  • 22. Committee Member for Admissions and Selection, School of Medicine, Chung Shan Medical University
  • 23. Interviewer and Application Reviewer for School of Medicine Admissions, Chung Shan Medical University
  • 24. Interview Committee Member for Graduate Institute of Medicine Admissions, Chung Shan Medical University
  • 25. Item Writer for the Written Examination in Board Certification of the Taiwan Urological Association
  • 26. Director of Summer Research, School of Medicine, Chung Shan Medical University
  • 27. Ministry of Education Teaching Qualification Review Committee Member (External Reviewer)
  • 28. Review Committee Member, National Science and Technology Council
  • 29. Examiner for the OSCE in the Physician National Licensing Examination
  • 30. Reviewer for the Paper Award of the Taiwan Medical Development Foundation
  • 31. Reviewer for Urological Papers at the Annual Conference of the Taiwan Surgical Association
  • 32. Reviewer for the Physiology Paper Competition at the Joint Annual Conference of Biomedical Science
  • 33. Master’s and Doctoral Degree Examination Committee Member
  • 34. Director, Human Biological Database Management Center
  • 35. Member, Medical Research Committee
  • 36. Member, Academic Ethics Committee
  • 37. Member, Medical Record Management Committee
  • 38. Member, Institutional Review Board for Human Research
  • 39. Independent Consultant, Institutional Review Board for Human Research
  • 40. Judge for the Evergent Tien-Te Lee Medical Science and Technology Award
  • 41. Best International Presentation Award, Japanese Urological Association
  • 1. Prostate Diseases: benign prostatic hyperplasia (enlarged prostate), laser prostate surgery, Da Vinci minimally invasive surgery for prostate cancer, and HIFU (High-Intensity Focused Ultrasound)
  • 2. Urinary Tract Stones: extracorporeal shock wave lithotripsy (ESWL), flexible ureteroscopic treatment, and minimally invasive endoscopic kidney stone surgery
  • 3. Hernia: minimally invasive laparoscopic hernia surgery
  • 4. Urinary Tract Tumors: Da Vinci minimally invasive surgery for urological tumors.
  • 5. Pediatric Urology: circumcision, hydrocele, hernia, and undescended testicle
  • 1. 【Journal Editorial Board Member or Guest Editor】Urological Science (Executive Editor, TUA official journal)／Frontiers in Cell and Developmental Biology／Cells／Frontiers in Molecular Biosciences／Journal of Personalized Medicine／World Journal of Gastrointestinal Oncology／PLOS ONE／Medicine (Section Editor)
  • 2. 【Journal Article Reviewer】International Journal of Cancer, Cancer, Cancers, Aging, International Journal of Molecular Sciences, Biomolecules, Frontiers in Immunology, Frontiers in Oncology, World Journal of Gastroenterology, World Journal of Gastrointestinal Oncology, Journal of Personalized Medicine, Tumor Biology, PLOS ONE, BMJ Open, Journal of Clinical Pathology, Therapeutics and Clinical Risk Management, Current Oncology, Reports, Microorganisms, Medicine, Symmetry, Pathology - Research and Practice, Applied Sciences, World Journal of Surgical Oncology, International Journal of Environmental Research and Public Health, Clinica Chimica Acta, Journal of Pediatric Neurology, Chinese Journal of Physiology, Clinical Medicine Insights: Oncology, Asian Journal of Urology, Public Health, Meta Gene, Brain Sciences, Medical Science Monitor, Journal of Oral Pathology and Medicine, Oncotarget, Technology in Cancer Research & Treatment, Journal of Clinical Laboratory Analysis, World Journal of Clinical Oncology, Asia-Pacific Journal of Clinical Oncology, World Journal of Clinical Cases, World Journal of Radiology, Journal of Clinical Trials, Biomedical Research, Advanced Materials Science Research, Journal of Medical & Surgical Pathology, Journal of Gastroenterology and Its Complications, Cancer Science & Research: Open Access, Acta Medica Philippina, JSM Surgical Oncology and Research, EBioMedicine, Journal of Clinical & Experimental Cardiology, Hepatology and Pancreatic Science, Dentistry Journal
  • 3.
  • 4. 【Research Grants and Projects】Principal Investigator: Establishing a tumor recurrence model after intravesical chemotherapy in a genotoxic carcinogen induced bladder cancer model to explore key therapeutic targets (Phase I project): Culturing primary cells to enhance tumor purity and improve the accuracy and reproducibility of subsequent analyses. Chung Shan Medical University Hospital (2025/01/01~2025/12/31)
  • 5. 【Research Grants and Projects】Principal Investigator: Explore the synergistic effects of isoalantolactone in combination with target therapies and immune checkpoint inhibitors in renal cell carcinoma: therapeutic strategies from doublet to triplet therapies. (113-2314-B-040-023-, 2024/08/01~2025/07/31)
  • 6. 【Research Grants and Projects】Principal Investigator: Therapeutic role of MET and AXL inhibitor, NPS-1034, in renal cell carcinoma (project part III): investigation of triplet therapy. Chung Shan Medical University Hospital (2024/01/01~2024/12/31)
  • 7. 【Research Grants and Projects】Principal Investigator: Therapeutic roles of crebanine in renal cell carcinoma by inducing cancer cell apoptosis. Chung Shan Medical University-Changhua Christian Hospital (CSMU-CCH-112-07, 2023/08/01~2024/07/31)
  • 8. 【Research Grants and Projects】Principal Investigator: Explore the synergistic effects of a dual c-Met/AXL inhibitor in combination with target therapies and immunotherapies in renal cell carcinoma: therapeutic strategies from doublet to triplet therapies. (NSTC 112-2314-B-040-010-, 2023/08/01~2024/07/31)
  • 9. 【Research Grants and Projects】Principal Investigator: Therapeutic roles of crebanine in glioblastoma multiforme by promoting cell death across the blood–brain barrier. Chung Shan Medical University-Chi Mei Medical Center (CMCSMU11102, 2022/10/01~2023/09/31)
  • 10. 【Research Grants and Projects】Principal Investigator: Isoalantolactone suppresses tumor malignancy through members of the TNF receptor superfamily and immunoglobulin superfamily in renal cell carcinoma: Exploring the molecular mechanism and synergistic effects with target therapies. National Science and Technology Council (NSTC 111-2314-B-040-033-, 2022/09/01~2023/08/31)
  • 11. 【Research Grants and Projects】Principal Investigator: Therapeutic role of MET and AXL inhibitor, NPS-1034, in renal cell carcinoma: explore mechanism and combination strategies. Chung Shan Medical University Hospital (2023/01/01~2023/12/31)
  • 12. 【Research Grants and Projects】Co-Principal Investigator: Synergistic role of Azacitidine combined with histone deacetylase inhibitors via intravesical instillation in bladder cancer. Chung Shan Medical University Hospital (2023/01/01~2023/12/31)
  • 13. 【Research Grants and Projects】Co-Principal Investigator: The therapeutic role of Odoroside A in the combination with chemotherapy regimens in pancreatic cancer: from tumor cells to transgenic mice model. Chung Shan Medical University Hospital (2023/01/01~2023/12/31)
  • 14. 【Research Grants and Projects】Co-Principal Investigator: PNU-74654 suppresses pancreatic cancer malignancy by induction of cell cycle arrest and inhibition of the epithelial-mesenchymal transition. CSMU-TSMH (CSMU-TSMH-111-02, 2022/09/01~2023/08/31)
  • 15. 【Research Grants and Projects】Co-Principal Investigator: Investigate the potential chemoprotective effect of melatonin in cisplatin plus gemcitabine induced side effects. Chung Shan Medical University Hospital (2022/01/01~2022/12/31)
  • 16. 【Research Grants and Projects】Co-Principal Investigator: Melatonin suppresses tumor malignancy in urothelial carcinoma. Chung Shan Medical University Hospital (2021/01/01~2021/12/31)
  • 17. 【Research Grants and Projects】Co-Principal Investigator: Mechanism of mast cell stabilizer to slow the pathological progression of interstitial cystitis. Chung Shan Medical University Hospital (2021/01/01~2021/12/31)
  • 18. 【Research Grants and Projects】Co-Principal Investigator: Role of WISP1/2 and related genes in promoting tumor malignancy of liver and colorectal cancer. Chung Shan Medical University Hospital (2020/01/01~2020/12/31)
  • 19. 【Research Grants and Projects】Co-Principal Investigator: Cardio-respiratory training improves immune surveillance through modification of lung microenvironments: evidence in primary tumor model of renal cancer. Chung Shan Medical University Hospital (2020/01/01~2020/12/31)
  • 20. 【Research Grants and Projects】Principal Investigator: Chidamide overcomes drug resistance to mitomycin C via attenuating DNA repair ability in intravesical instillation model for urothelial carcinoma: from molecular mechanism to clinical evidence. Ministry of Science and Technology (108-2314-B-040-014-MY3, 2019/08/01~2022/07/31)
  • 21. 【Research Grants and Projects】Co-Principal Investigator: Coenzyme Q contributes to bladder remodeling via modulation of microenvironment in interstitial cystitis model. Ministry of Science and Technology (108-2314-B-040-015-, 2019/08/01~2020/07/31)
  • 22. 【Research Grants and Projects】Co-Principal Investigator: Evaluation the therapeutic role of platelet-rich plasma in interstitial cystitis. Ministry of Science and Technology (107-2314-B-040-008-, 2018/08/01~2019/07/31)
  • 23. 【Research Grants and Projects】Principal Investigator: The therapeutic role of Azacitidine in chemoresistant bladder cancer. Chung Shan Medical University Hospital (2018/01/01~2018/12/31)
  • 24. 【Research Grants and Projects】Principal Investigator: Evaluation the therapeutic role of histone deacetylase inhibitors in chemoresistant bladder cancer via intravesical instillation. Ministry of Science and Technology (106-2314-B-040-026-MY2, 2017/10/01~2019/09/30)
  • 25. 【Research Grants and Projects】Principal Investigator: Evaluation of the prognostic role and its molecular mechanism of KLF17 in oral cancer. Chung Shan Medical University Hospital (2017/01/01~2017/12/31)
  • 26.
  • 27.
  • 28. 【2025 Publications】Wu YC, Wang SI, Lu LY, Wu MY, Wu PL, Hsieh TY, Sung WW. The Predictive Role of the Gleason Score in Determining Prognosis to Systematic Treatment in Metastatic Castration-Sensitive Prostate Cancer: A Systematic Review and Network Meta-Analysis. J Clin Med. 2025 Feb 17;14(4):1326.
  • 29. 【2024 Publications】Chang YC, Liu CT, Yu CY, Sung WW*. NPS-1034 Exerts Therapeutic Efficacy in Renal Cell Carcinoma Through Multiple Targets of MET, AXL, and TNFRSF1A Signaling in a Metastatic Model. Cells. 2024 Oct 17;13(20):1713. (*corresponding author)
  • 30. 【2024 Publications】Sung MT, Huang HE, Chang YC, Yu CY, Luo HL*, Sung WW*. Anticancer Potential of Isoalantolactone in Testicular Cancer: An Analysis of Cytotoxicity, Apoptosis, and Signaling Pathways. Aging (Albany NY). (accepted) (*corresponding author)
  • 31. 【2024 Publications】Chen TY, Chang YC, Yu CY, Sung WW*. Targeting the Adenosine A2A Receptor as a Novel Therapeutic Approach for Renal Cell Carcinoma: Mechanisms and Clinical Trial Review. Pharmaceutics. 2024, 16(9), 1127. (*corresponding author)
  • 32. 【2024 Publications】Wu YC, Sung WW*. Clomiphene Citrate Treatment as an Alternative Therapeutic Approach for Male Hypogonadism: Mechanisms and Clinical Implications. Pharmaceuticals (Basel). 2024 Sep 18;17(9):1233. (*corresponding author)
  • 33. 【2024 Publications】Chang YC, Yu CY, Dong C, Chen SL, Sung WW*. Divergent histopathological and molecular patterns in chemically induced interstitial cystitis/bladder pain syndrome rat models. Sci Rep. 2024 Jul 12;14(1):16134. (*corresponding author)
  • 34. 【2024 Publications】Luan YZ, Wang CC, Yu CY, Chang YC, Sung WW*, Tsai MC*. The Therapeutic Role of NPS-1034 in Pancreatic Ductal Adenocarcinoma as Monotherapy and in Combination with Chemotherapy. Int. J. Mol. Sci. 2024 Jun, 25(13), 6919. (*corresponding author)
  • 35. 【2024 Publications】Yeh PS, Liu CT, Yu CY, Chang YC, Lin SY, Li YC, Luan YZ*, Sung WW*. Crebanine, an aporphine alkaloid, induces cancer cell apoptosis through PI3K-Akt pathway in glioblastoma multiforme. Front Pharmacol. 2024 Jun 04, 15:1419044. (*corresponding author)
  • 36. 【2024 Publications】Wu MY, Luo HL, Chang YC, Yu CY, Sung WW*. Exercise may improve lung immunity after surgical stress: evidence from a nephrectomy model via a bioinformatic analysis. PLoS One. 2024 Jun 7;19(6):e0303334. (*corresponding author)
  • 37. 【2024 Publications】Yang TH, Chang YC, Yu CY, Sung WW*, Lee TH* Correlation Between CT Density, Incidence, Mortality, and Mortality-to-Incidence Ratio in Central Nervous System Cancers: An Exploratory Analysis of Global Data. In Vivo. 2024 Jul-Aug;38(4):2024-2030. (*corresponding author)
  • 38. 【2024 Publications】Chang NW, Huang YH, Sung WW, Chen SL. Adjuvant Chemotherapy in Patients with Locally Advanced Upper Tract Urothelial Carcinoma with or without Kidney Transplantation. J Clin Med. 2024 Mar 22;13(7):1831.
  • 39. 【2024 Publications】Shih CH, Lin YH, Luo HL, Sung WW*. Antibody-drug conjugates targeting HER2 for the treatment of urothelial carcinoma: potential therapies for HER2-positive urothelial carcinoma. Front Pharmacol. 2024 Mar 20;15:1326296. (*corresponding author)
  • 40. 【2024 Publications】Wang CC, Huang JY, Weng LH, Hsu YC, Sung WW, Huang CY, Lin CC, Wei JC, Tsai MC. Association between Cholecystectomy and the Incidence of Pancreaticobiliary Cancer after Endoscopic Choledocholithiasis Management. Cancers (Basel). 2024 Feb 28;16(5):977.
  • 41. 【2023 Publications】Tsai MC, Yen HH, Tsai HY, Huang YK, Luo YS, Kornelius E, Sung WW, Lin CC, Tseng MH, Wang CC. Artificial intelligence system for the detection of Barrett's esophagus. World J Gastroenterol. 2023 Dec 28;29(48):6198-6207.
  • 42. 【2023 Publications】Wang SC, Hsu HC, Chang YC, Yu CY, Liu CT, Sung WW*. Melatonin Exhibits Partial Protective Effects against Gemcitabine- and Cisplatin-Induced Kidney and Reproductive Injuries in Mice. Aging (Albany NY). 2023 Dec 14;15(23):14372-14383. (*corresponding author)
  • 43. 【2023 Publications】Sung WW*. Re: Wei Shen Tan, Ian M. McElree, Facundo Davaro, et al. Sequential Intravesical Gemcitabine and Docetaxel Is an Alternative to Bacillus Calmette-Guérin for the Treatment of Intermediate-risk Non-muscle-invasive Bladder Cancer. Eur Urol Oncol. 2023 Sep 5:S2588-9311(23)00171-2. (*corresponding author)
  • 44. 【2023 Publications】Chien TL, Wu YC, Lee HL, Sung WW, Yu CY, Chang YC, Lin CC, Wang CC, Tsai MC. PNU-74654 Induces Cell Cycle Arrest and Inhibits EMT Progression in Pancreatic Cancer. Medicina (Kaunas). 2023 Aug 24;59(9):1531.
  • 45. 【2023 Publications】Dong C, Sung WW*. Characterization of Gender Differences in H-index Within Urological Subspecialties. Letter. J Urol. 2023 Oct;210(4):585. (*corresponding author)
  • 46. 【2023 Publications】Peng CK, Wang SC, Chen SL*, Sung WW*. Multimodal Biomarkers That Predict the Presence of Gleason Pattern 4: Potential Impact for Active Surveillance. Letter. J Urol. 2023 Oct;210(4):580-581. (*corresponding author)
  • 47. 【2023 Publications】Hsiao PR, Sung WW*. Re: Disparities and Trends in Genitourinary Cancer Incidence and Mortality in the USA. Eur Urol. 2023 Jul;84(1):117-126. Eur Urol. 2023 Jul 22:S0302-2838(23)02970-6. (*corresponding author)
  • 48. 【2023 Publications】Peng CK, Sung WW*. Pathological and Clinical Outcomes in a Large Surveillance and Intervention Cohort of Radiographically Cystic Renal Masses. J Urol. 2023 Sep;210(3):408-409. (*corresponding author)
  • 49. 【2023 Publications】Ho CJ, Huang YH, Hsieh TY, Yang MH, Wang SC, Chen WJ, Sung WW, Chen SL. New Hydronephrosis in the Native Kidney Is Associated with the Development of De Novo Urinary Bladder Urothelial Carcinoma in Patients with Post-Kidney Transplantation. Healthcare (Basel). 2023 Apr 23;11(9):1209.
  • 50. 【2023 Publications】Lu XP, Sung WW, Weng JH, Weng JH, Hsia JY, Kao PF. Bladder Distention Demonstrating Vesicourachal Diverticulum on 18 F-FDG PET/CT Images of a Lung Cancer Patient. Clin Nucl Med. 2023 Jul 1;48(7):610-611.
  • 51. 【2023 Publications】Hsieh TY#, Sung WW#, Chang YC, Yu CY, Lu LY, Dong C, Lee TH, Chen SL. Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma. Aging (Albany NY) (IF: 5.68; Q2). 2023 Apr 21;15. (#equal contribution)
  • 52. 【2023 Publications】Peng CK, Sung WW*, Chen SL*. Clinical Efficacy of Neoadjuvant Intravesical Mitomycin-C Therapy Immediately Before Transurethral Resection of Bladder Tumor in Patients With Nonmuscle-invasive Bladder Cancer: Preliminary Results of a Prospective, Randomized Phase II Study. Letter. J Urol. 2023 Mar 9. (*corresponding author)
  • 53. 【2023 Publications】Wang YT, Chen BS, Wu HR, Chang YC, Yu CY, Sung WW*. Favorable Mortality-to-Incidence Ratio Trends of Lung Cancer in Countries with High Computed Tomography Density. Medicina (Kaunas). 2023 Feb 9;59(2):322. (*corresponding author)
  • 54. 【2023 Publications】Chen KY, Chen SL, Sung WW*. Re: Yosuke Yasuda, J.J.H. Zhang, Worapat Attawettayanon, et al. Comprehensive Management of Renal Masses in Solitary Kidneys. Eur Urol Oncol. 2023 Feb 16. (*corresponding author)
  • 55. 【2023 Publications】Peng CK, Sung WW*. Urinary Analysis of FGFR3 and TERT Gene Mutations Enhances Performance of Cxbladder Tests and Improves Patient Risk Stratification. Letter. J Urol. 2023 Apr;209(4):676-677. (*corresponding author)
  • 56. 【2023 Publications】Su CC, Chen BS, Chen HH, Sung WW, Wang CC, Tsai MC. Improved Trends in the Mortality-to-Incidence Ratios for Liver Cancer in Countries with High Development Index and Health Expenditures. Healthcare (Basel). 2023 Jan 4;11(2):159.
  • 57. 【2023 Publications】Wang CC, Su CC, Huang YP, Huang WH, Tsai TY, Sung WW, Yang TW, Lin JT, Lin CC, Yen HH, Tsai MC. Subsequent Cholecystectomy Improve Recurrent Biliary Event-Free Survival in High-Risk Acute Cholecystitis Patients after Gallbladder Drainage. Adv Dig Med. 2023; 1-8.
  • 58. 【2023 Publications】Chen KY, Wang SC, Chen SL, Sung WW*. A Comparison of Percutaneous Ablation Therapy to Partial Nephrectomy for cT1a Renal Cancers: Results From the Canadian Kidney Cancer Information System. Letter. J Urol. 2023 Apr;209(4):675. (*corresponding author)
  • 59. 【2022 Publications】Dong C, Fu JT, Wu HR, Chao YC, Chen YC, Sung WW, Chen WJ, Chen CJ. Mortality-to-Incidence Ratio for Nasopharyngeal Carcinoma Is Associated with Health Expenditure. Healthcare (Basel). 2022 Aug 25;10(9):1615.
  • 60. 【2022 Publications】Peng CK, Tsao CH, Sung WW, Wang SC, Chen WJ, Hsieh TY, Yang MH, Lee TH, Chen SL. The Impact of Transoral Robotic Surgery on Erectile Dysfunction and Lower Urinary Tract Symptoms in Male Patients with Moderate-to-Severe Obstructive Sleep Apnea. Healthcare (Basel). 2022 Aug 26;10(9):1633.
  • 61. 【2022 Publications】Wu MY, Wang CC, Chang YC, Yu CY, Sung WW, Chen CJ, Tsai MC. The Therapeutic Role of PNU-74654 in Hepatocellular Carcinoma May Involve Suppression of NF-κB Signaling. Medicina 2022 Jun 14;58(6):798.
  • 62. 【2022 Publications】Chen WJ#, Sung WW#, Yu CY, Luan YZ, Chang YC, Chen SL, Lee TH. PNU-74654 Suppresses TNFR1/IKB Alpha/p65 Signaling and Induces Cell Death in Testicular Cancer. Curr. Issues Mol. Biol. 2022, 44(1), 222-232. (#equal contribution)
  • 63. 【2022 Publications】Yen YA, Wang CC, Sung WW, Fang KC, Huang SM, Lin CC, Tsai MC, Yang TW. Intragastric injection of botulinum toxin A for weight loss: A systematic review and meta-analysis of randomized controlled trials. J Gastroenterol Hepatol. 2022 Apr 5. 2022 Jun;37(6):983-992.
  • 64. 【2022 Publications】Chen JT, Wang SC, Chen BS, Chang YC, Yu CY, Sung WW*, Song TY*. NPS-1034 Induce Cell Death with Suppression of TNFR1/NF-κB Signaling in Testicular Cancer. Medicina (Kaunas). 2022 Feb 27;58(3):355. (*corresponding author)
  • 65. 【2022 Publications】Dong C, Chen SL, Sung WW*. Re: Karin Welén, Ebba Rosendal, Magnus Gisslén, et al. A Phase 2 Trial of the Effect of Antiandrogen Therapy on COVID-19 Outcome: No Evidence of Benefit, Supported by Epidemiology and In Vitro Data. Eur Urol. 2022;81:285-293. Eur Urol. 2022 May;81(5):e123. (*corresponding author)
  • 66. 【2022 Publications】Wang SC, Yu CY, Wu YC, Chang YC, Chen SL, Sung WW*. Chidamide and mitomycin C exert synergistic cytotoxic effects against bladder cancer cells in vitro and suppress tumor growth in a rat bladder cancer model. Cancer Lett. 2022 Apr 1;530:8-15. (*corresponding author)
  • 67. 【2022 Publications】Yang TW, Wang CC, Sung WW, Ting WC, Lin CC, Tsai MC. The effect of coffee/caffeine on postoperative ileus following elective colorectal surgery: a meta-analysis of randomized controlled trials. Int J Colorectal Dis. 2022 Mar;37(3):623-630.
  • 68. 【2021 Publications】Wang CC, Sung WW, Yan PY, Ko PY, Tsai MC. Favorable colorectal cancer mortality-to-incidence ratios in countries with high expenditures on health and development index: A study based on GLOBOCAN database. Medicine (Baltimore). 2021 Oct 15;100(41):e27414.
  • 69. 【2021 Publications】Ho CJ, Huang YH, Hsieh TY, Yang MH, Wang SC, Chen WJ, Lee TH, Sung WW, Chen SL. Native Kidney Hydronephrosis Is Associated with Upper Urinary Tract Urothelial Carcinoma in Post-Kidney Transplantation Patients. J Clin Med. 2021 Sep 28;10(19):4474.
  • 70. 【2021 Publications】Wang SC, Chang YC, Wu MY, Yu CY, Chen SL, Sung WW*. Intravesical instillation of azacitidine suppresses tumor formation through TNF-R1 and TRAIL-R2 signaling in genotoxic carcinogen-induced bladder cancer. Cancers (Basel). 2021 Aug 4;13(16):3933. (*corresponding author)
  • 71. 【2021 Publications】Yang TW, Wang CC, Hung WC, Liu YH, Sung WW, Tsai MC. Improvement in the Mortality-to-Incidence Ratios for Gastric Cancer in Developed Countries With High Health Expenditures. Front Public Health. 2021 Aug 17;9:713895.
  • 72. 【2021 Publications】Sung WW#, Hsu YC#, Dong C, Chen YC, Chao YC, Chen CJ. Favorable Lip and Oral Cancer Mortality-to-Incidence Ratios in Countries with High Human Development Index and Expenditures on Health. Int J Environ Res Public Health. 2021 Jun 3;18(11):6012. (#equal contribution)
  • 73. 【2021 Publications】Lin KY, Su TC, Yeh CM, Chao WR, Sung WW*. High Expression of MTA1 Predicts Unfavorable Survival in Patients With Oral Squamous Cell Carcinoma. In Vivo. 2021 Jul-Aug;35(4):2363-2368. (*corresponding author)
  • 74. 【2021 Publications】Sung WW#, Au KK#, Wu HR, Yu CY, Wang YC. Improved trends of lung cancer mortality-to-incidence ratios in countries with high healthcare expenditure. Thorac Cancer. 2021 Jun;12(11):1656-1661. (#equal contribution)
  • 75. 【2021 Publications】Wu MY, Yang MH, Sung WW*. The treatment of renal cell carcinoma with the c-met inhibitor cabozantinib: mechanisms and clinical trials. Int J Clin Exp Med 2021 May;14(5):1831-1842. (*corresponding author)
  • 76. 【2021 Publications】Chia KJ, Lin LH, Sung MT, Su TM, Huang JF, Lee HL, Sung WW, Lee TH. Acute spontaneous thoracic epidural hematoma associated with intraspinal lymphangioma: A case report. World J Clin Cases. 2021 May 16;9(14):3411-3417.
  • 77. 【2021 Publications】Wang CC, Tseng MH, Wu SW, Yang TW, Chen HY, Sung WW, Su CC, Wang YT, Chen WL, Lai HC, Lin CC, Tsai MC. Symptomatic cholelithiasis patients have an increased risk of pancreatic cancer: A population-based study. J Gastroenterol Hepatol. 2021 May;36(5):1187-1196.
  • 78. 【2021 Publications】Yu WN, Lin HF, Lee YI, Shia WC, Sung WW, Yeh CM, Lin YM. PBK Expression Is Associated with Prognosis of Patients with Oral Squamous Cell Carcinoma Treated With Radiotherapy: A Retrospective Study. Anticancer Res. 2021 Apr;41(4):2177-2182.
  • 79. 【2021 Publications】Lan C, Sung WW, Ho SW. Man With Fever and Groin Mass. Ann Emerg Med. 2021 Apr;77(4):e93-e94.
  • 80. 【2021 Publications】Wang CC, Tseng MH, Wu SW, Yang TW, Sung WW, Wang YT, Lee HL, Shiu BH, Lin CC, Tsai MC. The Role of Series Cholecystectomy in High Risk Acute Cholecystitis Patients Who Underwent Gallbladder Drainage. Front Surg. 2021 Feb 15;8:630916.
  • 81. 【2021 Publications】Huang CY, Wang SC, Chan L, Hsieh TY, Sung WW*, Chen SL*. Gender differences in trends of bladder cancer mortality-to-incidence ratios according to health expenditure in 55 countries. PLoS One. 2021 Feb 12;16(2): e0244510. (*corresponding author)
  • 82. 【2021 Publications】Wang SC, Chang NW, Chen WJ, Yang MH, Chen SL*, Sung WW*. Trends of Testicular Cancer Mortality-to-Incidence Ratios in Relation to Health Expenditure: An Ecological Study of 54 Countries. Int J Environ Res Public Health. 2021 Feb 6;18(4):1546. (*corresponding author)
  • 83. 【2021 Publications】Sung WW, Ko PY, Chen WJ, Wang SC, Chen SL. Trends in the kidney cancer mortality-to-incidence ratios according to health care expenditures of 56 countries. Sci Rep. 2021 Jan 14;11(1):1479.
  • 84. 【2021 Publications】Huang RH, Yang WK, Wu CM, Yeh CM, Sung WW*. Over-expression of CEP55 Predicts Favorable Prognosis in Colorectal Cancer Patients with Lymph Node Involvement. Anticancer Research 2021; 41 (1): 543-547. (*corresponding author)
  • 85. 【2020 Publications】Yeh CM, Lee YJ, Ko PY, Lin YM*, Sung WW*. High Expression of KLF10 Is Associated with Favorable Survival in Patients with Oral Squamous Cell Carcinoma. Medicina (Kaunas). 2020 Dec 28;57(1):E17. (*corresponding author)
  • 86. 【2020 Publications】Wang CC, Tseng MH, Wu SW, Yang TW, Chen HY, Sung WW, Su CC, Wang YT, Lin CC, Tsai MC. Cholecystectomy reduces subsequent cholangiocarcinoma risk in choledocholithiasis patients undergoing endoscopic intervention. World J Gastrointest Oncol. 2020 Dec 15;12(12):1381-1393.
  • 87. 【2020 Publications】Wang SC, Chan L, Hsieh ZY, Wang CH, Chen SL, Sung WW*. Limited improvement in prostate cancer mortality-to-incidence ratios in countries with high health care expenditures. Aging (Albany NY). 2020 Nov 12;12(21):21308-21315. (*corresponding author)
  • 88. 【2020 Publications】Lin YM, Chen ML, Chen CL, Yeh CM, Sung WW*. Overexpression of EIF5A2 Predicts Poor Prognosis in Patients with Oral Squamous Cell Carcinoma. Diagnostics (Basel). 2020 Jun 27;10(7):E436. (*corresponding author)
  • 89. 【2020 Publications】Wang CC, Yang TW, Sung WW, Tsai MC. Current Endoscopic Management of Malignant Biliary Stricture. Medicina (Kaunas). 2020 Mar 5;56(3). pii: E114.
  • 90. 【2020 Publications】Lee YJ, Chan L, Yeh CM, Lee CH*, Sung WW*. Overexpression of KLF17 Predicts a Favorable Prognosis in Patients with Oral Squamous Cell Carcinoma: A Retrospective Study. Medicina (Kaunas). 2020 Jan 30;56(2). pii: E57. (*corresponding author)
  • 91. 【2019 Publications】Chen WJ, Huang CY, Huang YH, Wang SC, Hsieh TY, Chen SL, Sung WW*, Lee TH*. Correlations between Mortality-to-Incidence Ratios and Health Care Disparities in Testicular Cancer. Int J Environ Res Public Health. 2019 Dec 23;17(1). pii: E130. (*equal contribution)
  • 92. 【2019 Publications】Yang TH, Chang CS, Sung WW, Liu JT. Lumboperitoneal Shunt: A New Modified Surgical Technique and a Comparison of the Complications with Ventriculoperitoneal Shunt in a Single Center. Medicina (Kaunas). 2019 Sep 26;55(10). pii: E643.
  • 93. 【2019 Publications】Lee TH#, Sung WW#, Chan L, Lee HL, Chen SL, Huang YH, Kwan AL. The Association between Mortality-to-Incidence Ratios and Health Expenditures in Brain and Nervous System Cancers. Int J Environ Res Public Health. 2019 Jul 31;16(15). pii: E2739. (#equal contribution)
  • 94. 【2019 Publications】Wang CC, Tsai MC, Wang SC, Peng CM, Lee HL, Chen HY, Yang TW, Lin CC*, Sung WW*. Favorable Gallbladder Cancer Mortality-To-Incidence Ratios of Countries with Good Ranking of World’s Health System and High Expenditures on Health. BMC Public Health. 2019 Jul 31;19(1):1025. (*corresponding author)
  • 95. 【2019 Publications】Chen ML, Ho CJ, Yeh CM, Sung WW, Chen SL, Wang SC, Chen CJ. High SPOCK1 expression is associated with advanced stage, T value, and Gleason grade in prostate cancer. Medicina. 2019 Jul 5;55(7). pii: E343.
  • 96. 【2019 Publications】Lee TH, Huang YH, Su TM, Chen CF, Lu CH, Lee HL, Tsai HP, Sung WW*, Kwan AL*. Predictive Factors of 2-Year Postoperative Outcomes in Patients with Spontaneous Cerebellar Hemorrhage. J Clin Med. 2019 Jun 8;8(6). pii: E818. (*corresponding author)
  • 97. 【2019 Publications】Wang CC, Tsai MC, Sung WW, Yang TW, Chen HY, Wang YT, Su CC, Tseng MH, Lin CC. Risk of cholangiocarcinoma in patients undergoing therapeutic endoscopic retrograde cholangiopancreatography or cholecystectomy: A population based study. World J Gastrointest Oncol. Mar 15, 2019; 11(3): 238-249.
  • 98. 【2019 Publications】Wang CC, Tsai MC, Wang YT, Yang TW, Chen HY, Sung WW, Huang SM, Tseng MH, Lin CC. Role of Cholecystectomy in Choledocholithiasis Patients Underwent Endoscopic Retrograde Cholangiopancreatography. Sci Rep. 2019 Feb 18;9(1):2168.
  • 99. 【2018 Publications】Huang CY, Au KK, Chen SL, Wang SC, Liao CY, Hsu HH, Sung WW*, Wang YC*. Unfavorable Mortality-To-Incidence Ratio of Lung Cancer is Associated with Health Care Disparity. Int J Environ Res Public Health. 2018 Dec 13;15(12). pii: E2889. (*corresponding author)
  • 100. 【2018 Publications】Su TC, Chen CY, Tsai WC, Hsu HT, Yen HH, Sung WW*, Chen CJ*. Cytoplasmic, Nuclear, and Total PBK/TOPK Expression is Associated with Prognosis in Colorectal Cancer Patients: a Retrospective Analysis Based on Immunohistochemistry Stain of Tissue Microarrays. PLoS One. 2018 Oct 4;13(10):e0204866. (*corresponding author)
  • 101. 【2018 Publications】Tsai MC, Yang TW, Wang CC, Wang YT, Sung WW, Tseng MH, Lin CC. Favorable clinical outcome of nonalcoholic liver cirrhosis patients with coronary artery disease: A population-based study. World J Gastroenterol. 2018 Aug 21;24(31):3547-3555.
  • 102. 【2018 Publications】Sung WW, Wang SC, Hsieh TY, Ho CJ, Huang CY, Kao YL, Chen WJ, Chen SL. Favorable mortality-to-incidence ratios of kidney cancer are associated with advanced health care systems. BMC Cancer. 2018 Aug 6;18(1):792.
  • 103. 【2018 Publications】Lee HL, Peng CM, Huang CY, Wu SY, Tsai MC, Wang CC, Chen SL, Lin CC, Huang CN, Sung WW*. Is mortality-to-incidence ratio associated with health disparity in pancreatic cancer? A cross-sectional database analysis of 57 countries. BMJ Open. 2018 Jul 6;8(7):e020618. (*corresponding author)
  • 104. 【2018 Publications】Chang CC, Sung WW, Hsu HT, Yeh CM, Lee CH, Chen YL, Liu YC, Yeh KT. Validation of EGFL6 expression as a prognostic marker in lung adenocarcinoma patients in Taiwan: a retrospective study. BMJ Open. 2018 Jun 22;8(6):e021385.
  • 105. 【2017 Publications】Tsai MC, Wang CC, Lee HL, Peng CM, Yang TW, Chen HY, Sung WW*, Lin CC*. Health Disparities Are Associated with Gastric Cancer Mortality-To-Incidence Ratios in 57 Countries. World J Gastroenterol. 2017 Nov 28;23(44):7881-7887. (*corresponding author)
  • 106. 【2017 Publications】Wang CC, Tsai MC, Peng CM, Lee HL, Chen HY, Yang TW, Sung WW*, Lin CC*. Favorable Liver Cancer Mortality-To-Incidence Ratios of Countries with High Health Expenditure. Eur J Gastroenterol Hepatol. 2017 Dec;29(12):1397-1401. (*corresponding author)
  • 107. 【2017 Publications】Wang SC#, Sung WW#, Kao YL, Hsieh TY, Chen WJ, Chen SL, Chang HR. The gender difference and mortality-to-incidence ratio relate to health care disparities in bladder cancer: National estimates from 33 countries. Sci Rep. 2017 Jun 28;7(1):4360. (#equal contribution)
  • 108. 【2017 Publications】Hsu LS, Huang RH, Lai HW, Hsu HT, Sung WW, Hsieh MJ, Wu CY, Lin YM, Chen MK, Lo YS, Chen CJ. KLF6 inhibited oral cancer migration and invasion via downregulation of mesenchymal markers and inhibition of MMP-9 activities. Int J Med Sci. 2017 Apr 9;14(6):530-535.
  • 109. 【2017 Publications】Chen CJ, Sung WW, Chen HC, Chern YJ, Hsu HT, Lin YM, Lin SH, Peck K, Yeh KT. Early Assessment of Colorectal Cancer by Quantifying Circulating Tumor Cells in Peripheral Blood. Int J Mol Sci. 2017 Mar 31;18(4). pii: E743.
  • 110. 【2017 Publications】Su HA, Sun PL, Sung WW, Cheng SY, Chang HC, Yang JH, Hsiao YP. Deep Dermatophytosis Caused by Zoophilic Strain of Trichophyton interdigitale with Successful Treatment of Itraconazole. Mycopathologia. 2017 Aug;182(7-8):715-720.
  • 111. 【2017 Publications】Chen SL, Wang SC, Ho CJ, Kao YL, Hsieh TY, Chen WJ, Chen CJ, Wu PR, Ko JL, Lee H, Sung WW*. Prostate Cancer Mortality-To-Incidence Ratios Are Associated with Cancer Care Disparities in 35 Countries. Sci Rep. 2017 Jan 4;7:40003. (*corresponding author)
  • 112. 【2017 Publications】Chiu LY, Hsin IL, Yang TY, Sung WW, Chi JY, Chang JT, Ko JL, Sheu GT. The ERK-ZEB1 pathway mediates epithelial-mesenchymal transition in pemetrexed resistant lung cancer cells with suppression by vinca alkaloids. Oncogene. 2017 Jan 12;36(2):242-253.
  • 113. 【2016 Publications】Chang CF, Chen SL, Sung WW, Hsieh MJ, Hsu HT, Chen LH, Chen MK, Ko JL, Chen CJ, Chou MC. PBK/TOPK Expression Predicts Prognosis in Oral Cancer. Int J Mol Sci. 2016 Jun 24;17(7). pii: E1007.
  • 114. 【2016 Publications】Lee CH, Chen SL, Sung WW, Lai HW, Hsieh MJ, Yen HH, Su TC, Chiou YH, Chen CY, Lin CY, Chen ML*, Chen CJ*. The Prognostic Role of STEAP1 Expression Determined via Immunohistochemistry Staining in Predicting Prognosis of Primary Colorectal Cancer: A Survival Analysis. Int J Mol Sci. 2016 Apr 19;17(4). pii: E592.
  • 115. 【2016 Publications】Yeh CM#, Sung WW#, Lai HW, Hsieh MJ, Yen HH, Su TC, Chang WH, Chen CY, Ko JL, Chen CJ. Opposing Prognostic Roles of Nuclear and Cytoplasmic RACGAP1 Expression in Colorectal Cancer Patients. Hum Pathol. 2016 Jan;47(1):45-51. (#equal contribution)
  • 116. 【2015 Publications】Lin YM#, Sung WW#, Hsieh MJ, Tsai SC, Lai HW, Yang SM, Shen KH, Chen MK, Lee H, Yeh KT, Chen CJ. High PD-L1 Expression Correlates with Metastasis and Poor Prognosis in Oral Squamous Cell Carcinoma. PLoS One. 2015 Nov 12;10(11):e0142656. (#equal contribution)
  • 117. 【2015 Publications】Hwang JC, Sung WW, Tu HP, Hsieh KC, Yeh CM, Chen CJ, Tai HC, Hsu CT, Shieh GS, Chang JG, Yeh KT, Liu TC. The Overexpression of FEN1 and RAD54B May Act as Independent Prognostic Factors of Lung Adenocarcinoma. PLoS One. 2015 Oct 2;10(10):e0139435.
  • 118. 【2014 Publications】Sung WW, Lin YM, Wu PR, Yen HH, Lai HW, Su TC, Huang RH, Wen CK, Chen CY, Chen CJ, Yeh KT. High nuclear/cytoplasmic ratio of Cdk1 expression predicts poor prognosis in colorectal cancer patients. BMC Cancer. 2014 Dec 15;14:951.
  • 119. 【2014 Publications】Wu DW, Chuang CY, Lin WL, Sung WW, Cheng YW, Lee H. Paxillin promotes tumor progression and predicts survival and relapse in oral cavity squamous cell carcinoma by microRNA-218 targeting. Carcinogenesis. 2014 Aug;35(8):1823-9.
  • 120. 【2013 Publications】Sung WW and Lee H. The Role of Interleukin-10 in Tumor Progression of Human Papillomavirus-Associated Non-Small Cell Lung Cancer. OncoImmunology. 2013 Sep 1;2(9):e25854.
  • 121. 【2013 Publications】Sung WW, Wang YC, Lin PL, Cheng YW, Chen CY, Wu TC, Lee H. IL-10 Promotes Tumor Aggressiveness via Upregulation of CIP2A Transcription in Lung Adenocarcinoma. Clin Cancer Res. 2013 Aug 1;19(15):4092-103. (CCR Highlights)
  • 122. 【2013 Publications】Wang YC#, Sung WW#, Wang L, Cheng YW, Chen CY, Wu TC, Shieh SH, Lee H. Different Impact of IL10 Haplotype on Prognosis in Lung Squamous Cell Carcinoma and Adenocarcinoma. Anticancer Res. 2013 Jun;33(6):2729-35. (#equal contribution)
  • 123. 【2013 Publications】Tang SC, Wu CH, Lai CH, Sung WW, Yang WJ, Tang LC, Hsu CP, Ko JL. Glutathione s-transferase mu2 suppresses cancer cell metastasis in non-small cell lung cancer. Mol Cancer Res. 2013 May;11(5):518-29.
  • 124. 【2013 Publications】Chen CJ, Sung WW, Su TC, Chen MK, Wu PR, Yeh KT, Ko JL, Lee H. High expression of interleukin 10 might predict poor prognosis in early stage oral squamous cell carcinoma patients. Clin Chim Acta. 2013 Jan 16;415:25-30.
  • 125. 【2012 Publications】Chen CJ, Sung WW, Lin YM, Chen MK, Lee CH, Lee H, Yeh KT, Ko JL. Gender difference in the prognostic role of interleukin 6 in oral squamous cell carcinoma. PLoS One. 2012;7(11):e50104.
  • 126. 【2012 Publications】Chuang CY#, Sung WW#, Wang L, Lin WL, Yeh KT, Su MC, Hsin CH, Lee SY, Wu BC, Cheng YW, Lee H. Differential impact of IL-10 expression on survival and relapse between HPV16-positive and -negative oral squamous cell carcinomas. PLoS One. 2012;7(10):e47541. (*equal contribution)
  • 127. 【2012 Publications】Chen TH, Huang CC, Yeh KT, Chang SH, Chang SW, Sung WW, Cheng YW, Lee H. Human papilloma virus 16 E6 oncoprotein associated with p53 inactivation in colorectal cancer. World J Gastroenterol. 2012 Aug 14;18(30):4051-8.
  • 128. 【2012 Publications】Wang YC#, Sung WW#, Wu TC, Wang L, Chien WP, Cheng YW, Chen CY, Shieh SH, Lee H. Interleukin-10 haplotype may predict survival and relapse in resected non-small cell lung cancer. PLoS One. 2012;7(7):e39525. (#equal contribution)
  • 129. 【2012 Publications】Tsai LL, Yu CC, Lo JF, Sung WW, Lee H, Chen SL, Chou MY. Enhanced cisplatin resistance in oral-cancer stem-like cells is correlated with upregulation of excision-repair cross-complementation group 1. J Dent Sci. 2012 Jun; 7(2):111–7.
  • 130. 【2011 Publications】Sung WW, Wang YC, Cheng YW, Lee MC, Yeh KT, Wang J, Chen CY, Lee H. A polymorphic -844T/C in fasl promoter predicts survival and relapse in non-small cell lung cancer. Clin Cancer Res. 2011 Sep 15;17(18):5991-9. (CCR Highlights)
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